产品货号:
Z17730
中文名称:
HDAC4 (internal)抗体
英文名称:
Anti-HDAC4 (internal) Antibody
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HDAC4 (internal) Antibody |
指标别名 | HA6116;HD4;HDAC A;HDAC4;HDACA;histone deacetylase 4;KIAA0288 |
克隆性 | Polyclonal |
检验物种 | human,mouse,primate,rat |
应用范围 | WB |
基因名称 | HDAC4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | HDAC4 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region surrounding 600-650aa of human HDAC4. |
成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,50% (v/v) Glycerol, |
纯化方式 | Anti-HDAC4 was affinity purified from monospecific antiserum by immunoaffinity chromatography.This antibody is specific towards HDAC4.A BLAST analysis was used to suggest cross-reactivity with Human,Mouse,Rat,and Primate based on 100% sequence homology.Cross-reactivity with HDAC4 from other sources has not been determined. |
浓度 | 1mg/mL by UV absorbance at 280nm |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is six (6) months from date of opening. |
背景资料 | HDAC4 is a 140kD class II histone deacetylase similar to the yeast HDA1 protein.This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues.HDAC activity has been associated with transcriptional repression and nucleosomal condensation.HDAC4 uses active nuclear export to shuttle between the nucleus and the cytoplasm.HDAC4 is modified by phosphorylation by CaM kinase I or IV.HDAC4 has been reported to interact with 14-3-3 in the cytoplasm and MEF2A,HDAC3,NcoR and SMRT in the nucleus.Anti-HDAC4 antibodies are ideal for researchers interested in Breast Cancer,Cancer,Cell Cycle and Replication,Chromatin Research,Epigenetics,and Histone Deacetylases research. |
Uniprot ID | P56524 |
推荐稀释比 | ELISA:1:20,000 - 1:60,000 IHC:1mg/mL IF Microscopy:1:100~1:500 WB:1mg/mL |
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